Its primary clinical discussion centers on its role in telomere biology, where research suggests it may influence telomerase activity, the enzyme responsible for maintaining telomere length
Back to Journals Drug Design, Development and Therapy Volume 18 Oral Bioavailability, Tissue Distribution, Metabolism, and Excretion of Panduratin A from Boesenbergia rotunda Extract in Healthy Rats Authors Kongratanapasert T, Boonyarattanasoonthorn T, Supannapan K, Hongeng S, Khemawoot P Received 7 December 2023 Accepted for publication 5 June 2024 Published 11 July 2024 Volume 2024:18 Pages 29052917 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Professor Manfred Ogris Teetat Kongratanapasert, 1, 2 Tussapon Boonyarattanasoonthorn, 3 Kittitach Supannapan, 4 Suradej Hongeng, 5 Phisit Khemawoot 1 1 Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samutprakarn, Thailand

What has been reported in the available human pilot research is that no significant adverse effects were observed - which is a meaningful data point for safety consideration, even if it does not establish efficacy by clinical standards
Rhodiola Rhodiola is an adaptogenic herb that helps the body cope with stress